Rus Articles Journal

Rozeola of pink

Modern children and parents quite often face one of diseases which often becomes the reason of bewilderment of doctors. Besides, manifestations are very similar to other states that becomes the reason of wrong diagnostics. Doctors of policlinics make the diagnosis a rubella or an allergy again and again though the disease it is known not one century. What there is a speech about? It is about the rozeol pink.

In what the reason?

the Reason of development of this disease - herpes 6 types. On our planet there are about 100 different types of herpes. Probably, fortunately, but at the person only 8 is till today allocated. But also these 8 are quite enough.

of Herpesvirus 6 (HHV - 6) it is widespread on Earth, and till 2 years causes the infectious disease which is characterized by high fever and a number of other clinical manifestations which become the reason of nervousness of parents in children.

the Virus of herpes of the 6th type is one of the main reasons not only addresses to the district doctor of policlinic, but also calls of crews of “emergency medical service“ during infancy. Herpes is capable to cause complications from the central nervous system.

In spite of the fact that after an illness the herpes virus completely disappears, DNA of a virus can remain still very long in blood, saliva, cerebrospinal fluid and not to prove in any way. However, it can not always be so. Further in the course of growth of the child or at the adult if there are states which are followed by decrease in immunity, the virus can become more active or, joining a virus of herpes 7, to cause limfoproliferativny diseases, a glandular fever and mononukleoz.

to Rozeol`s

pink already davny - long ago it is known worldwide. As Gog, he is Yura, he is Gosha, the rozeola has several names. Mother can meet such names as a sudden ekzantema (the name speaks about sudden emergence of characteristic rash), a sudden ekzantema of children of early age, a pseudo-rubella (pseudorubella), the sixth illness, three-day fever, roseola infantum, exanthema subitum.

B 1870 of Meigs and Pepper were described by the children`s diseases shown ekzantemy (rash on skin), and called them ’ roseola aestiva ’ or ’ roseola autumnalis (summer rozeola and rozeola autumn). Judging by their description, most likely it was roseola infantum (a children`s rozeola). However, rank the American pediatrician Zagorski as the first who in 1910 described a rozeola pink (Zahorsky J.) . Later, v1941 to year of Breese conducted the first perspective research of a rozeola in which described the characteristic, a clinical and laboratory picture and that is important, defined age group ill (mainly children aged from 6 months till 3 years). Supervision of the doctor allowed to assume that the infecting agent is widespread everywhere, but the illness proceeds more often asymptomatically. Statistical data say that in the first 3 months of life children suffer from a sudden ekzantema extremely seldom. This fact allowed to state a hypothesis that children have protection thanks to passive protection by mother`s antibodies.

Still later, in 1988, Yamanishi for the first time allocated from blood of 4 patients sudden ekzantemy babies the causative agent of a disease - a virus of herpes of the 6th type (Herpesvirus 6 (HHV - 6)).

by what

B to the country would not conduct researches, HHV - 6 was found everywhere, as gave the grounds to draw a conclusion on universal distribution of a virus. In the majority of the countries the peak of incidence of HHV - the 6th infection is the share of age from 6 to 18 months, with an average value about 9 months.

At the birth each baby possesses mother`s antibodies which protect it. But their level considerably decreases by 4 months of life of the kid, and, therefore, the child becomes susceptible to an infection. Further increase in a share of children with antibodies to a virus of herpes of the 6th type shows us with what speed children get an infection by 1,5 years. Why the infection so quickly extends among children of early age, for the present it is fully not found out, but most likely, continuous contact with a virus is the reason. And an infection source, most likely, - elderly and the adults who are in continuous contact with the child. Once met, the virus remains in the child`s organism, circulating in blood, a secret of airways and other liquids.

two options of a virus of herpes 6 types Exist: option A (HHV - 6A) and option B (HHV - 6B). In saliva there are both options, but HHV - 6B at bigger quantity.

of the Rash and other symptoms of an infection develop, apparently, from - for HHV - 6B of strains. Therefore, it is possible to assume that this option has more transmissivnost or infektivnost, than option A (i.e. it is more infectious).

Plus to it the virus can probably infect with

the kid vnutriutrobno and during the perinatal period. To these assumptions scientists came because HHV genome - 6 was found in peripheral blood of healthy newborns and in cervical allocations of pregnant women. However breastfeeding, apparently, is not one of the main ways of transfer.

Clinical manifestations of primary HHV - 6 infections

the Main symptom of primary infection caused by herpes 6 types - a rozeola or, in a different way, a sudden ekzantema. For this reason the disease carries such name. However clinical manifestations can be various. In half of cases the disease begins brightly and suddenly. Fever which sometimes reaches 40 degrees or even above develops. Then temperature decreases within 3 - 6 days. Rise in temperature is caused by presence of a virus at blood. During this period the child becomes irritable, sluggish and refuses food. In classical option fever lasts three days. From there is one of names - three-day fever. When temperature decreases, it becomes much easier for the kid.

After decrease in temperature on skin the ekzantema appears - pink it is spotty - the papular rashes of 1 - 3 mm which are turning pale when pressing. They can disappear in several hours, and can remain about several days. Rash is localized mainly on the case, extending to a neck, a face and extremities.

Other symptom of a gerpesvirusny infection of the 6th type is the limfadenopatiya which takes all cervical knots, but increase in occipital knots during the first 3 days is most characteristic. In addition sometimes Nagayana spots - an ekzantema of a soft palate and a uvula appear. Still such signs as, for example, a vybukhayushchy fontanel or spasms can accompany Rozeola. But usually the illness proceeds not so hard.

At children 3 years are more senior than

and adults herpes of the 6th type becomes more active, as a rule, at an immunosupressiya (decrease in immunity).

Diagnostics of primary HHV - 6 infections

Laboratory diagnostics of a rozeola pink is reduced by

to blood test and identification of a virus by means of serologichesky research. But not specific, decrease in total of leukocytes, neutrophils and lymphocytes during the first several days of an illness is characteristic, reaching the lowest point for the 4th day. In spite of the fact that now many serologichesky tests are available, exact detection of a virus remains difficult.

of Complication of an infection of herpes 6 types

the Clinical course of primary gerpesvirusny infection often do not demand hospitalization from healthy children. However, as it is specified in one of researches, 13% of children with primary gerpesny infection of the 6th type were hospitalized with suspicion on sepsis.

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the Main complications of primary HHV - 6 infections are connected with impact of a virus on the central nervous system (CNS). Most often parents face spasms. Less often the vybukhaniye of a big fontanel or an encephalomeningitis meets. More often complications arise at children with primary infection aged from 12 till 15 months.

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It was proved that after primary infection the virus remains in tserebrospinalny liquid. Stability of DNA of a virus of herpes of the 6th type is connected with emergence of periodic attacks at children.

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Treatment

Experts estimated sensitivity of a human virus of herpes 6 to various antiviral agents (mainly polymerase DNA inhibitors).

In spite of the fact that preparations (An acyclovir and Gantsiklovir), were tested on several patients with the weakened immunity, their clinical efficiency remained is not clear. Now no concrete preparations for treatment of a disease are recommended. Therefore in treatment only symptomatic means are used.

needs to create the guarding mode to the child. Whenever possible hold the kid in a bed, especially if he has a high temperature. Increase the volume of the drunk liquid. At high temperature use febrifuges. Listen to recommendations of the doctor in the choice of medicines. The main method of prevention of an illness - immunity maintenance. Observe all recommendations made by doctors, you monitor food of the kid, conduct active lives, accept polyvitaminic preparations and the illness will avoid.